General NM case of the month (07/09): Splenosis on SPECT-CT
This case was compiled by Dr. Joji Varghese, MEDVAMC
A 60 yrs old male, smoker, with a past medical history of hypertension, and
remote h/o post trauma splenectomy presented with symptoms of UTI. He
was found to have microscopic hematuria which did not resolve with
antibiotics and a CT scan of the abdomen was performed. It showed multiple
enhancing soft tissue density masses in the abdomen and pelvis.
Splenosis was suspected and a liver-spleen scan was acquired after the
injection of 8.7 mCi of Tc-99m sulfur colloid. Planar images showed multiple
scattered foci of increased uptake in the abdomen and pelvis, consistent with
splenosis. SPECT-CT images showed that all the enhancing lesions seen on
the diagnostic CT corresponded to foci of increased uptake, consistent with
splenic tissue.
1. Splenosis: 99mTc-labelled colloids provide the diagnosis in
splenectomised patients. Franceschetto A, Casolo A, Cucca M, Bagni B.
Eur J Nucl Med Mol Imaging. 2006 Sep;33(9):1102.

2. Splenosis presenting as multiple intra-abdominal masses mimicking
malignancy.Kok J, Lin M, Lin P, Ngu C, Sam S, Loh C, Kociuba K. ANZ
J Surg. 2008 May;78(5):406-7.
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