PET-CT case of the month (08/09): Mesothelioma
This case was compiled by Dr. David He (BCM) and Dr. Joji Varghese (MEDVAMC)
61 yrs old male presented with c/o productive cough for 3 months. He was
initially treated with antibiotics for possible pneumonia, but without success.
Subsequent chest CT found extensive pleural based soft tissue density
encasing the right lung with possible mediastinal and diaphragmatic
invasion, suspicious for mesothelioma.
initially treated with antibiotics for possible pneumonia, but without success.
Subsequent chest CT found extensive pleural based soft tissue density
encasing the right lung with possible mediastinal and diaphragmatic
invasion, suspicious for mesothelioma.
PET-CT images show intense linear FDG uptake surrounding the right lung
and extending into the right hemidiaphragm, corresponding to the soft
tissue density on CT, max SUV measuring 9.5, consistent with
mesothelioma. Multiple hypermetabolic nodes seen in the mediastium and
the upper abdomen are consistent with metastatic disease.
and extending into the right hemidiaphragm, corresponding to the soft
tissue density on CT, max SUV measuring 9.5, consistent with
mesothelioma. Multiple hypermetabolic nodes seen in the mediastium and
the upper abdomen are consistent with metastatic disease.
1. The role of positron emission tomography/computed tomography in the
diagnosis of pleural diseases. Orki A, Akin O, Tasci AE, Ciftci H, Urek S,
Falay O, Kutlu CA Thorac Cardiovasc Surg. 2009 Jun;57(4):217-21.
2. 18F-fluoro-2-deoxy-D-glucose positron emission tomography and
positron emission tomography/computed tomography imaging of malignant
pleural mesothelioma. Subramaniam RM, Wilcox B, Aubry MC, Jett J,
Peller PJ. J Med Imaging Radiat Oncol. 2009 Apr;53(2):160-9
3. Morphologic and functional imaging of malignant pleural mesothelioma.
Yamamuro M, Gerbaudo VH, Gill RR, Jacobson FL, Sugarbaker DJ,
Hatabu H Eur J Radiol. 2007 Dec;64(3):356-66.
diagnosis of pleural diseases. Orki A, Akin O, Tasci AE, Ciftci H, Urek S,
Falay O, Kutlu CA Thorac Cardiovasc Surg. 2009 Jun;57(4):217-21.
2. 18F-fluoro-2-deoxy-D-glucose positron emission tomography and
positron emission tomography/computed tomography imaging of malignant
pleural mesothelioma. Subramaniam RM, Wilcox B, Aubry MC, Jett J,
Peller PJ. J Med Imaging Radiat Oncol. 2009 Apr;53(2):160-9
3. Morphologic and functional imaging of malignant pleural mesothelioma.
Yamamuro M, Gerbaudo VH, Gill RR, Jacobson FL, Sugarbaker DJ,
Hatabu H Eur J Radiol. 2007 Dec;64(3):356-66.
